An update of the Guangzhou Twin Eye Study

The Guangzhou Twin Eye Study(GTES)is a population-based study of young twins residing in Guangzhou City.The major aim of GTES is to explore the impact of genes,environmental factors and gene-environment interactions on common eye diseases.From 2006,for more than 1,300 twin pairs,age 7-26 years old,progressive ocular phenotypes,such as refraction,ocular biometrics,weight,and height were collected annually,while non-progressive phenotypes such as parental refraction,corneal thickness,retinal fundus,intraocular pressure and DNA only collected at baseline.In the current study,we summarize the major findings on the etiology of myopia in recent decades.