摘要
肠道菌群与慢性乙型肝炎(CHB)存在密切关系。近年研究表明,肠道菌群的失调与CHB病情的发生、发展及预后有关,且随着疾病的进展,肠道菌群环境也可能发生变化,二者相互影响,相互作用。本文综述了肠道菌群影响CHB及其相关肝病的病情发展和菌群的调节在CHB及其相关肝病诊治中的作用,以期为CHB的临床治疗提供新思路。
Intestinal flora is closely associated with chronic hepatitis B(CHB).Recent studies have shown that the imbalance of intestinal flora is associated with the development,progression,and prognosis of CHB,and the environment of intestinal flora may also change with disease progression,suggesting that intestinal flora and CHB interact with each other.This article reviews the influence of intestinal flora on the progression of CHB and related liver diseases and the role of intestinal flora regulation in the diagnosis and treatment of CHB and related liver diseases,in order to provide new ideas for the clinical treatment of CHB.
作者
郭紫薇
张嘉鑫
李硕
李晓斌
朱顺
靳茜
李小科
叶永安
GUO Ziwei;ZHANG Jiaxin;LI Shuo;LI Xiaobin;ZHU Shun;JIN Qian;LI Xiaoke;YE Yongan(Department of Gastroenterology and Hepatology,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;The First Clinical Medical College of Beijing University of Chinese Medicine,Beijing 100029,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2022年第5期1137-1142,共6页
Journal of Clinical Hepatology
基金
国家科技重大专项“十三五”课题(2018ZX10725505)
国家自然科学基金青年科学基金项目(81804033)。
关键词
乙型肝炎
慢性
肝硬化
胃肠道微生物组
粪菌移植
Hepatitis B,Chronic
Liver Cirrhosis
Gastrointestinal Microbiome
Fecal Microbiota Transplantation
