橙皮苷生物学活性及其改性技术的研究进展

Research Progress on Biological Activity and Modification Technology of Hesperidin

橙皮苷是一种广泛存在于柑橘属水果中的天然黄酮类化合物,具有抗氧化、抗炎、抑菌和抗癌等多种生物活性。已有研究表明,橙皮苷因其水溶性和吸收性较差,导致生物利用度较低,因此国内外学者聚焦于橙皮苷进行物理、化学和生物改性,以增加其溶解性及生物利用度。本文对橙皮苷的生物学活性、改性技术以及改性衍生物的相关内容进行综述,为橙皮苷的高效利用提供理论支撑。

Hesperidin, a natural flavanone, predominantly existed in citrus fruit, has many biological functions, such as antioxidant, anti-inflammatory, bacteriostasis and anti-cancer. Current research suggests that hesperidin possesses a lower bioavailability due to its poor water solubility and absorption. Therefore, more and more attention from domestic and foreign scholars has been focused on physical, chemical and biological modification of hesperidin to increase its solubility and bioavailability. In this paper, the biological activity, modification technology and modification derivatives of hesperidin are reviewed to provide theoretical support for the efficient utilization of hesperidin.