摘要
睡眠是人体最重要的生理活动之一,儿童处于生长发育的关键时期,良好的睡眠可提高机体免疫力,与神经系统发育、学习及记忆功能密切相关。而睡眠医学中,儿童神经科常见的睡眠障碍问题,常常作为共患病的发生,对儿童对认知、情感、生长发育等多方面造成损害。睡眠障碍的病理生理改变主要为神经递质的改变。神经递质分为兴奋性和抑制性两类,当其含量的变化超过生理范围时,就会发生病变,出现睡眠障碍的临床表现。本文着重介绍睡眠障碍相关神经系统的研究机制及现状,提高对睡眠障碍的评估及干预水平,优化疾病管理,改善患儿的睡眠情况,提高患儿生活质量。
Sleep is one of the most important physiological activities of the human body.Childhood is a critical period of growth and development.A good sleep can improve the body's immunity,which is closely related to the development of the nervous system,learning and memory functions.Sleep disorder is a common problem in pediatric neurology,which may occur alone or with other neurological diseases,causing damage to children's cognition,emotion,growth and development.The pathophysiological changes of sleep disorders mainly include neurotransmitter changes.Neurotransmitters can be divided into excitability and inhibition.When the change of their content exceeds the physiological range,pathological changes will occur and clinical manifestations of sleep disorders will appear.This paper mainly introduces the research mechanism and status of the nervous system related to sleep disorders,aiming to improve the evaluation and intervention level of sleep disorders,optimize disease management,improve sleep conditions of children and improve their quality of life.
作者
柳佳彤
吴琼
王华
LIU Jiatong;WU Qiong;WANG Hua(Shengjing Hospital of China Medical University,Shenyang 110000,China)
出处
《中国中西医结合儿科学》
2022年第2期120-122,共3页
Chinese Pediatrics of Integrated Traditional and Western Medicine
基金
中国抗癫痫协会UCB基金项目(2020009B)
省博士科研启动基金计划项目(2019-BS-280)。