胃肠道间质瘤危险度分级与CT征象的相关性分析

Correlation analysis of risk grade and CT signs of gastrointestinal stromal tumor

目的:探讨CT对胃肠道间质瘤(gastrointestinal stromal tumors,GISTs)危险度的预测价值。方法:经病理证实的43例GISTs进行回顾性研究,分析预测GISTs危险度的独立因素。结果:43例GISTs,胃壁来源35例,小肠来源8例,所有病例均为单发。低危组21例(含极低危GISTs 3例),中危组10例,高危组12例。单因素分析结果显示,将肿瘤大小、形状、生长方式、强化类型、杂乱血管征对比研究,差异存在统计学意义(P<0.05)。多因素分析结果显示,不均匀强化(OR=2.936,95%CI:0.86~5.00)、杂乱血管征(OR=2.669,95%CI:0.84~4.49)是预测GISTs危险度的独立因素(P<0.05)。结论:CT征象对预测GISTs的危险度具有重要参考价值。

Objective:To explore the value of computed tomography(CT)in predicting the risk degree of GISTs.Methods:43 cases of GISTs that confirmed by pathology were studied retrospectively,to analyze the independent factors which can predict the risk degree of GISTs.Results:Among the 43 cases,35 cases occurred in stomach,the other 8 cases occurred in small intestine,and all cases were single.There were 21 cases in the low-risk group(including 3 very low-risk cases),10 cases in the middle-risk group and 12 cases in the high-risk group.The results of univariate analysis showed that there were statistically significant differences in tumor size,shape,growth mode,enhancement type and disordered vascular sign(P<0.05).The results of multivariate analysis showed that uneven enhancement(OR=2.936,95%CI:0.86~5.00)and disordered vascular sign(OR=2.669,95%CI:0.84~4.49)were independent factors for predicting the risk of GISTs(P<0.05).Conclusion:The CT signs plays an important role in predicting the risk degree of GISTs.