摘要
近年,因缺牙而接受牙种植术治疗的患者中,高血压患者占比居高不下,这对牙种植术的开展及维持治疗效果提出了较大挑战。本文总结高血压对种植牙产生不利影响的临床研究证据,归纳不同种类抗高血压药对骨代谢产生积极影响的分子机制,提出临床医师应根据高血压患者的血压值,在术前、术中选用不同的风险防控措施,以降低高血压患者行牙种植术的风险。
Recently,among the edentulous patients who undergo dental implants,the proportion of hypertensive patients remains high,which poses a greater challenge for clinicians to operate and to maintain the therapeutic effect.The present review comprehensively summarized clinical researches about the adverse effects on dental implants,outlined molecular mechanisms of the positive effects of various antihypertensive drugs on bone metabolism,and proposed that clinicians should select preventive strategies during preoperative and intraoperative procedures according to the blood pressure of patients with hypertension.
作者
许煜梓
王思源
周川
何福明
Xu Yuzi;Wang Siyuan;Zhou Chuan;He Fuming(Department of Prosthodontics,Stomatology Hospital,School of Stomatology,Zhejiang University School of Medicine&Clinical Research Center for Oral Diseases of Zhejiang Province&Key Laboratory of Oral Biomedical Research of Zhejiang Province&Cancer Center of Zhejiang University,Hangzhou 310006,China;Department of Orthodontics,Stomatology Hospital,School of Stomatology,Zhejiang University School of Medicine&Clinical Research Center for Oral Diseases of Zhejiang Province&Key Laboratory of Oral Biomedical Research of Zhejiang Province&Cancer Center of Zhejiang University,Hangzhou 310006,China)
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2022年第4期430-435,共6页
Chinese Journal of Stomatology
基金
浙江省科学技术厅重点研发计划项目(2019C03081)。
关键词
牙种植
高血压
抗高血压药
骨代谢
骨结合
Dental implantation
Hypertension
Antihypertensive agents
Bone metabolism
Osseointegration