肾康注射液不良反应分析

Analysis of adverse reactions of Shenkang injection

目的:通过对14例肾康注射液不良反应的分析,进一步探究此药品对人体的安全性作用,为临床医生合理用药提供参考依据。方法:通过对2016年1月-2021年6月所收集的肾康注射液ADR报告,采用回顾性研究方法进行分析。结果:肾康注射液所致ADR中,男女性别比为0.75:1,45岁以上中老年人群(占85.72%)为高发人群;ADR累及器官系统最多的为皮肤及其附件损害(32.00%),临床表现为斑丘疹、皮疹、皮肤潮红、红肿、瘙痒;其次为全身性损害(24.00%)、神经系统损害(20.00%)。新的不良反应有4例,一般的不良反应有10例,经过对症处理和治疗后都已好转或痊愈。结论:临床应重视不同患者个体差异,规范用药,加强用药全程监护可有效减少肾康注射液不良反应的发生,从而保障患者用药安全有效。

Objective:Through the analysis of 14 cases of adverse reactions of Shenkang injection,the safety effect of Shenkang injection on human body was further explored to provide a reference for the rational drug use of clinicians.Method:The ADR reports of Shenkang injection collected from January 2016 to June 2021 were analyzed by retrospective study method.Result:In ADR caused by Shenkang injection,the ratio of male to female was 0.75:1.The middle-aged and old people(85.72%)over 45 years old were the high incidence group.The most common ADRs involved organ systems were skin and its appendages(32.00%).The most common clinical manifestations were maculopapule,rash,skin flushing,redness and itching.The second were systemic damage(24.00%)and nervous system damage(20.00%).There were 4 cases of new adverse reactions and 10 cases of general adverse reactions,which were all improved or cured after symptomatic treatment and treatment.Conclusion:Clinical attention should be paid to the individual differences of different patients,standardized medication,and strengthened whole-course monitoring of medication which can effectively reduce the occurrence of adverse reactions of Shenkang injection,so as to ensure safe and effective medication for patients.