糖尿病患者颈动脉超声参数与FRS评分在评估动脉粥样硬化性心血管疾病中的价值

Value of carotid artery ultrasound parameters and Framingham Risk Score in reviewing atherosclerotic cardiovascular diseases in diabetic patients

目的分析糖尿病患者颈动脉超声参数与FRS评分在动脉粥样硬化性心血管疾病评估中的价值。方法选取2019年6月至2021年6月于我院心内科就诊的糖尿病患者108例为研究对象,其中单纯糖尿病患者53例设为对照组,合并冠状动脉粥样硬化性心脏病(冠心病)的糖尿病患者55例为观察组。采取FRS评估糖尿病患者冠心病的危险因素,颈动脉超声参数。结果两组患者在性别、年龄、体质指数(BMI)、冠心病家族史、左心室舒张末期内径、射血分数,差异均无统计学(P>0.05);观察组吸烟比例显著高于对照组,差异有统计学意义(P<0.05)。彩色多普勒超声检查中观察组患者斑块例数显著高于对照组,颈动脉内中膜厚度、斑块积分、FRS评分显著高于对照组,组间差异显著(P<0.05);观察组FRS患病风险显著高于对照组(P<0.05);二分类Logistic回归分析结果显示,FRS、颈动脉斑块与动脉粥样硬化性心血管疾病存在明显相关性(P<0.05)。结论糖尿患者FRS与颈动脉超声参数存在明显联系,可作为动脉粥样硬化性心血管疾病初步评估方式。

Objective To analyze the value of carotid artery ultrasound parameters and Framingham Risk Score(FRS)in reviewing atherosclerotic cardiovascular diseases in diabetic patients.Methods The diabetic patients(n=108)were chosen from Department of Internal Medicine in Hospital of Fuzhou Economic and Technological Development Zone from June 2019 to June 2021,and the patients with only diabetes were selected into control group(n=53)and those with diabetes complicated by coronary heart disease(CHD)were selected into observation group(n=55).The risk factors of CHD and carotid artery ultrasound parameters were reviewed by using FRS.Results The differences in gender,age,body mass index(BMI),CHD family history,left ventricular end-diastolic inner diameter(LVEDd)and left ventricular ejection fraction(LVEF)had no statistical significance between 2 groups(P>0.05),and percentage of smoking was higher in observation group than that in control group(P<0.05).The results of color Doppler ultrasonography showed that the cases of plaque were more,and carotid artery intima-media thickness(CA-IMT),plaque scores and FRS were significantly higher in observation group than those in control group(P<0.05).The risk of CHD was significantly higher in observation group than that in control group(P<0.05).The results of binary Logistic regression analysis showed that FRS,carotid artery plaque and atherosclerotic cardiovascular diseases were significantly correlated to each other(P<0.05).Conclusion There is a significant relationship between FRS and carotid artery ultrasound parameters,and FRS can be taken as an initial assessment method for atherosclerotic cardiovascular diseases.