乳腺硬化性腺病超声造影及超微血管成像表现的特征分析

Analysis of the features of contrast-enhanced ultrasound and ultramicrovascular imaging in breast sclerosing adenosis

目的 探讨乳腺硬化性腺病(sclerosing adenosis,SA)超声造影(contrast-enhanced ultrasound,CEUS)及超微血管成像的表现特征。方法 回顾性分析2017年12月—2021年12月于本院就诊的15例SA患者以及同期于本院诊治的40例乳腺浸润性导管癌(invasive ductal carcinoma,IDC)患者的CEUS及超微血管成像表现,结合病理分析SA的CEUS及超微血管成像特征。结果 在CEUS定性特征中,SA在增强强度、增强后病灶边缘、增强后充盈缺损、增强后病灶范围及血管形态分型等表现与IDC比较,差异有统计学意义(均P<0.05);在定量参数中,SA和IDC的峰值强度、曲线斜率、曲线下面积、流入面积、流出面积等比较,差异亦有统计学意义(均P<0.05)。结论 乳腺SA的超声造影及超微血管成像表现与IDC有明显差异,全面认识这些特征有助于提高超声诊断准确率。

ObjectiveTo investigate the features of contrast-enhanced ultrasound(CEUS) and ultramicrovascular imaging in breast sclerosing adenosis(SA).MethodsThe CEUS and ultramicrovascular imaging of 15 SA patients and 40 cases of infiltrating ductal carcinoma(IDC) patients admitted to Guangxi Medical University Cancer Hospital from December 2017 to December 2021 were analyzed retrospectively,and the CEUS and ultramicrovascular imaging features of SA were analyzed combined with pathological features.ResultsIn the qualitative features of CEUS,there were statistically significant differences between SA and IDC in enhancement intensity,lesion edge,perfusion defects,lesion scope and ultramicrovascular imaging architecture(all P<0.05).Among quantitative parameters,there were statistically significant differences between SA and IDC in peak intensity,curve slope,area under the curve,inflow area and outflow area(all P<0.05).ConclusionsThe certain characteristics in CEUS and ultramicrovascular imaging of breast SA are significantly different from IDC,and a comprehensive understanding of these features helps improve the diagnostic accuracy of breast sclerosing adenosis.