摘要
前列腺穿刺活检是前列腺癌诊断的金标准。PSMA PET是新兴的成像技术,对确诊有临床意义前列腺癌病灶具有较高临床价值,对局部复发、淋巴结转移等有较高的识别能力。PSMA PET影像融合引导前列腺靶向穿刺活检可提高有临床意义前列腺癌的检出率,协助选择前列腺癌骨转移的活检病灶,规划活检针道,提高转移性去势抵抗性前列腺癌患者骨活检的成功率。目前,相关研究较少,仍需前瞻性随机对照研究来探讨PSMA PET在前列腺癌靶向穿刺中应用的可行性。
Prostate biopsy is the gold standard for diagnosis of prostate cancer.Positron emission tomography(PET)of prostate-specific membrane antigen is a new imaging technology,which has high clinical value in the detection of Clinically Significant Prostate Cancer.It also has high recognition ability for local recurrence and lymph node metastasis.Targeted prostate biopsy guided by PSMA PET can improve the detection rate of clinically significant prostate cancer,help guide the selection of prostate cancer bone biopsy lesions,plan the needle path,and improve the success rate of bone biopsy in patients with mCRPC.However,prospective randomized controlled studies are still needed to explore the feasibility of PSMA PET in targeted biopsy of prostate cancer.
作者
黄琦
柯志滨
许宁
Huang Qi;Ke Zhibin;Xu Ning(Department of Urology,Urology Research Institute,the First Affiliated Hospital,Fujian Medical University,Fuzhou 350005,China)
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2022年第4期317-320,共4页
Chinese Journal of Urology
基金
福建省卫健委中青年骨干人才培养项目(2019-ZQN-54)
2021年福建省雏鹰计划青年拔尖人才经费(SCYJHBJRC-XN2021)。
关键词
前列腺肿瘤
前列腺特异性膜抗原
正电子发射计算机断层显像
磁共振成像
前列腺穿刺活检
Prostate neoplasms
Prostate specific membrane antigen
Positron emission tomography/computed tomography
Magnetic resonance imaging
Prostate biopsy