煤矿职工牙周病与代谢综合征的相关对照研究

Correlation study on periodontitis and metabolic syndrome in coal mine workers

目的 探讨煤矿职工牙周病与代谢综合征(metabolic syndrome,MS)之间的相关性。方法 2019年1-12月,随机抽取250名河北省开滦市某企业的煤矿职工(煤矿职工组)和30名同年龄段健康志愿者(对照组)为研究对象,分别进行问卷调查及口腔检查,收集参与者的基本临床资料及各项血液生化指标。将研究对象按照是否为MS[MS组和非代谢综合征组(nonmetabolic syndrome,Non-MS组)]及牙周病的严重程度[社区牙周指数(community periodontal index,CPI)从≥3开始]进行分组,比较各组间各项临床参数间的差异,分析牙周病和MS之间的关系。结果 对照组和煤矿职工组在体质指数(body mass index,BMI)、CPI评分和MS比例间差异均有统计学意义(均P<0.01),Non-MS组和MS组在煤矿职工的BMI、三酰甘油(triacylglycerol,TG)、空腹血糖(fasting blood glucose,FBG)和社区牙周指数(community periodontal index,CPI)评分≥3分的比例间差异均有统计学意义(均P<0.05);随煤矿职工CPI分值的增加,MS患病率显著增加(χ;=51.383,P<0.01),多因素和单因素回归分析显示CPI值为MS的影响因素,(OR=1.902,95%CI:1.670~2.402)。结论 开滦市煤矿职工牙周病与MS具有相关性,且该疾病的患病率与牙周病的严重程度正相关。

Objective To explore the correlation between periodontitis and metabolic syndrome(MS) in coal mine workers. Methods From January to December 2019,250 coal mine workers(coal mine workers group) from an enterprise and 30 healthy volunteers of the same age(control group) in Kailuan City of Hebei Province were randomly selected for questionnaire survey and oral examination,and the participants’ basic clinical data and various blood biochemical indicators were collected. The subjects were grouped according to whether they were metabolic syndrome(MS group and Non-MS group) and the severity of periodontitis [community periodontal index(CPI) ≥3],and the difference of clinical parameters between the groups were compared,the relationship between periodontitis and MS were analyzed. Results There were statistically significant differences in the body mass index(BMI),CPI score and MS ratio between the control group and the coal mine workers group(all P<0.01). There were statistically significant differences in BMI,triglyceride(TG),fasting blood glucose(FBG) and proportion of CPI score≥3 between the Non-MS group and the MS group(all P<0.05). With the increase of the CPI score of the coal mine workers,the prevalence of the MS was significantly increased(χ;=51.383,P<0.01). Multivariate and univariate regression analysis showed that the CPI value was an influencing factor of MS(OR =1.902,95% CI:1.670-2.402). Conclusion The periodontitis of coal mine workers in Kailuan city is related to MS,and the prevalence of MS is positively correlated with the severity of periodontitis.