眼缺血性疾病对脑卒中发生的预警作用

Early warning effect of ocular ischemic disease on stroke

目的探讨眼部缺血性疾病与脑卒中的相关性及预警作用。方法回顾性病例研究。分析2019年1~12月我院神经内科住院的患者200例为研究对象,记录患者颈动脉超声结果。对患者进行眼部检查,明确是否患有眼部缺血性疾病。了解研究对象的一般资料特征,采用SPSS17.0统计学软件比较不同性别、年龄、既往史、眼缺血性疾病等的脑卒中患病率。根据单因素分析结果,通过Logistic模型分析眼缺血性疾病与脑卒中的相关性。结果颈动脉超声正常者在冠心病、心房颤动、脑卒中病史、吸烟史及眼缺血性疾病临床表现均低于异常者(P<0.05)。颈动脉超声异常者脑卒中患病率明显高于正常者(P<0.01)。随着颈动脉狭窄程度的加重,脑卒中患病率、高血压病史、冠心病病史、心房颤动史、脑卒中病史、吸烟史及眼缺血性疾病临床表现发生率随之增加(P<0.05)。脑卒中患者高血压病史、冠心病病史、心房颤动病史、脑卒中病史、吸烟史及眼缺血性疾病临床表现患病率高于非脑卒中患者(P<0.01)。Logistics回归分析显示,高血压病史、冠心病病史、脑卒中病史、吸烟及眼缺血性疾病临床表现是脑卒中发生的正相关因素。结论脑卒中是常见的脑血管疾病,给家庭及社会均带来了沉重的负担。高血压病史、冠心病病史、脑卒中病史、吸烟及眼缺血性疾病临床表现是脑卒中发生的正相关因素。其中眼缺血性疾病与脑卒中相关性的发现为脑卒中发生的预警提供了新的思路。

Objective To investigate the correlation between ocular ischemic disease and stroke and to explore its early warning effect.Methods Retrospective case study.200 inpatients in the department of neurology of our hospital from January 2019 to December 2019 were selected in the ananlysis,and undewent the examination of carotid ultrasound and ocular ischemia.To understand the general data characteristics of the subjects,the prevalence of stroke in different gender,age,past history and ocular ischemic disease were tested by SPSS17.0 statistical software.According to the results of univariate analysis,the correlation between ocular ischemic disease and stroke was analysed by logistic model.Results The clinical manifestations of coronary heart disease,atrial fibrillation,stroke history,smoking history and ocular ischemic disease in patients with normal carotid ultrasound were less than those with abnormal carotid artery ultrasound(P<0.05).The incidence of stroke in patients with abnormal carotid ultrasound was significantly higher than that in normal subjects(P<0.01).The incidence of stroke,hypertension,coronary heart disease,atrial fibrillation,stroke,smoking and clinical manifestations of ocular ischemic disease increased as the aggravation of carotid artery stenosis,(P<0.05).The prevalence of hypertension,coronary heart disease,atrial fibrillation,stroke,smoking and clinical manifestations of ocular ischemic disease in stroke patients were higher than those in non-stroke patients(P<0.01).Logistic regression analysis showed that therer was a positive correlation between the hypertension history,coronary heart disease history,stroke history,smoking and clinical manifestations of ocular ischemic disease and stroke.Conclusions Stroke is a common cerebrovascular disease,which brings heavy burden to family and society.Hypertension history,coronary heart disease history,stroke history,smoking and clinical manifestations of ocular ischemic disease are positive factors associated with the occurrence of stroke.Among them,the discovery of the correlation between ocular ischemic disease and stroke provides a new idea for early warning of stroke.