金花茶化学成分和药理作用研究进展

Research progress on chemical constituents and pharmacological studies of Camellia nitidissima

金花茶Camellia nitidissima为我国广西地区的少数民族常用药,具有清热解毒、利尿消肿等功效。近年来,对于金花茶开展了大量的化学成分和药理学研究,表明金花茶含有黄酮类化合物、多糖、皂苷等多种生物活性成分,该植物及其提取物具有抗肿瘤、抗炎、抗氧化、调血脂、降血糖、抗肥胖、降血压、抗过敏、抗衰老等药理作用。对金花茶化学成分和药理研究进展进行了归纳总结,为更好地利用该植物和新药研发提供理论参考。

Camellia nitidissima is common traditional ethnic medicine in Guangxi,which takes effect by clearing away heat and toxic materials and diuretic detumescence.In recent years,a great number of chemical,and pharmacological studies on Camellia nitidissima Chi have been carried out,primarily in China.Phytochemical investigations have shown that the plant contains a rich source of bioactive constituents,including flavonoids,polysaccharides,saponins,and other components.Pharmacological studies have demonstrated that Camellia nitidissima Chi possesses anti-tumour,anti-inflammatory,antioxidant,hypolipidemic effect,hypoglycemic,anti-obesity,hypotensive,anti-anaphylaxis,and anti-aging properties.The present paper presents an up-to-date overview of the chemical constituents and pharmacological effects of Camellia nitidissima Chi in order to explore the potential of this plant for drug development.