外周血炎症指标与胰腺癌预后相关性的研究进展

Progress on the correlation between peripheral blood inflammatory index and the prognosis of pancreatic cancer

胰腺癌发病率在全球总体呈现上升趋势,具有早期诊断困难、常伴远处转移、外科切除率低、术后易复发等临床特点,预后亟待提高。研究已经证实,炎症与肿瘤发生密切相关,炎症介质在胰腺癌肿瘤微环境中发挥了重要作用,并影响胰腺癌预后。本文就外周血炎症指标与胰腺癌预后相关性的研究作一综述。

Globally,the incidence of pancreatic cancer is on a rise.Pancreatic cancer is characterized by difficulty in early diagnosis,frequent distant metastasis,low surgical resection rate,and high risk of postoperative recurrence.Better treatments need to be developed to prolong the prognosis.Studies have confirmed that inflammation is closely correlated with tumorigenesis,and inflammatory mediators play important roles on tumor microenvironment of pancreatic cancer and lead to poor prognosis.This article reviewed the progress on the correlation between peripheral blood inflammatory index and the prognosis of pancreatic cancer.