孤立性真皮黑素瘤5例临床及组织病理分析

Clinical and histopathological analysis of five cases of solitary dermal melanoma

目的分析孤立性真皮黑素瘤(SDM)的临床及组织病理特点。方法回顾性分析5例SDM患者的临床及组织病理学资料。结果SDM临床表现为黑色、肤色、红色的丘疹或结节,无特定好发部位。病理表现为局限性真皮/皮下孤立性结节,无明显包膜,具有恶性肿瘤的特征,表皮不受累。结论详细的临床资料以及皮肤组织病理学检查是正确诊断SDM的关键。

Objective To analysis clinical and histopathological features of solitary dermal melanoma(SDM).Methods Clinical and histopathological data were collected from 5 patients with SDM,and analyzed retrospectively.Results The 5 patients with SDM presented with black,skin-colored or red papules or nodules without any without any specific anatomic predilection.These lesions pathologically manifested as localized dermal/subcutaneous solitary nodules with characteristics of malignancy but no obvious capsules,and the epidermis was not involved.Conclusion Detailed clinical data and skin histopathological examination are the keys to accurate diagnosis of SDM.