自身免疫性疱病与银屑病的相关性

Correlation between autoimmune bullous diseases and psoriasis

自身免疫性疱病(AIBD)和银屑病的发病机制有部分相似性。近年来,多项研究报道银屑病与AIBD之间具有相关性,以大疱性类天疱疮多见,还包括寻常型天疱疮、红斑型天疱疮、线状IgA大疱性皮病等,多数AIBD在银屑病发病后发生,部分患者两病同时出现或AIBD先出现。本文综述AIBD与银屑病发病的相关性及可能存在的机制。

There are overlaps in pathogenesis between autoimmune bullous diseases(AIBDs)and psoriasis.In recent years,there have been many reports on correlations between psoriasis and AIBDs.Bullous pemphigoid is the most common AIBD associated with psoriasis,followed by pemphigus vulgaris,pemphigus erythematosus and linear IgA bullous dermatosis.AIBDs occur after the onset of psoriasis in most cases,but simultaneously with or before the onset of psoriasis in some patients.This review summarizes correlations between AIBDs and psoriasis,as well as possible mechanisms.