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EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma 被引量:1

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摘要 Platelet-derived growth subunit A(PDGFA)plays critical roles in development of glioblastoma(GBM)with substantial evidence from TCGA database analyses and in vivo mouse models.So far,only platelet-derived growth receptor a(PDGFRA)has been identified as receptor for PDGFA.However,PDGFA and PDGFRA are categorized into different molecular subtypes of GBM in TCGA_GBM database.
出处 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2022年第3期746-757,共12页 信号转导与靶向治疗(英文)
基金 This work was supported by:The National Key Research and Development Program of China(2017YFC1309004 to Y.W.) The National Natural Science Foundation of China(81972365 to Y.W.,81821003 to X.-W.B.,81602006 to F.-L.C.,and 81922056 to Y.S.) Chongqing Academician Program(cstc2019yszx-jcyjX0008 to Y.W.and cstc2018jcyj-yszxX0008 to X.-H.Y.).
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