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Targeting polarized phenotype of microglia via IL6/JAK2/ STAT3 signaling to reduce NSCLC brain metastasis 被引量:3

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摘要 Tumor-associated macrophages have emerged as crucial factors for metastases.Microglia are indispensable components of the brain microenvironment and play vital roles in brain metastasis(BM).However,the underlying mechanism of how activated microglia promote brain metastasis of non-small cell lung cancer(NSCLC)remains elusive.
出处 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2022年第3期869-880,共12页 信号转导与靶向治疗(英文)
基金 This work was supported by the National Natural Science Foundation of China(Grant no.81773360) the Engineering Research Center Innovation Capacity Building Project of Hubei(Grant no.2018-420114-35-03-071705) the National Independent Innovation Fund(Grant no.5003540112).
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