不同血液净化模式对合并急性肾损伤的危重患者治疗评价

Evaluation of Different Blood Purification Modes in the Treatment of Critical Patients Complicated with Acute Kidney Injury

目的:评价在急性肾损伤危重患者实施不同血液净化模式的效果。方法:评价对象选择于2019年3月-2021年1月时段就诊于某院的120例急性肾损伤危重患者,因血液净化模式差异性予以分组评价,分为实验组和对照组各60例,实验组采用连续性血液净化模式,对照组采用间歇性血液净化模式,比较和评价两种血液净化模式的实施效果。结果:对比对照组,实验组患者治疗总有效率显著提升,比较差异性显著(P<0.05);对比对照组,实验组肾功能指标(血尿素氮、血肌酐)均降低显著,比较差异性显著(P<0.05);对比对照组,实验组患者心率降低显著,平均动脉压提升显著,比较差异性显著(P<0.05);实验组患者电解质异常率显著低于对照组,比较差异性显著(P<0.05);实验组患者透析并发症总发生率显著低于对照组,比较差异性显著(P<0.05)。结论:对急性肾损伤危重患者实施连续性血液净化模式与间歇性血液净化模式相比效果更佳,可对患者肾功能发挥保护作用,可维持电解质平衡,减少并发症,可改善血流动力学,缓解肾损伤,建议推广。

Objective:To evaluate the effect of different blood purification modes in the treatment of critically ill patients complicated with acute kidney injury.Methods:120 critically ill patients with acute kidney injury treated in a hospital from March 2019 to January 2021 were selected and evaluated in groups due to the differences in blood purification modes.60 patients with the mode of continuous blood purification were included to the experimental group,and 60 cases of patients with intermittent blood purification mode were included into the control group.The implementation of the two kinds of mode of blood purification effect were compared and evaluated.Results:Compared with the control group,the total treatment effective rate of the experimental group was significantly improved,and the difference was significant(P<0.05).Compared with the control group and the experimental group,renal function indexes(blood urea nitrogen,serum creatinine)decreased significantly,and the difference was significant(P<0.05).Compared with the control group,the experimental group patients'heart rate decreased significantly,the mean arterial pressure increased significantly,and the difference was significant(P<0.05).Compared with the control group,the electrolyte abnormality rate in the experimental group was significantly reduced,and the difference was significant(P<0.05).Compared with the control group,the total incidence of dialysis complications in the experimental group was significantly reduced,and the difference was significant(P<0.05).Conclusion:The continuous blood purification mode is better than the intermittent blood purification mode in critically ill patients with acute kidney injury,which can play a protective role in renal function,maintain electrolyte balance,reduce complications,improve hemodynamics and alleviate renal injury,and is recommended to be promoted.