临床待输血患者RhE抗原和不规则抗体的检测及其临床意义

Detection and Clinical Significance of RhE Antigen and Irregular Antibody in Clinical Transfusion Patients

探究在临床待输血患者中予以RhE抗原和不规则抗体检测的应用效果与价值。方法:研究对象抽取血液中心督导的多家用血医院患者标本共200例,研究时间为2019年2月到2020年2月,所有患者均采用微柱凝胶法对其RhE抗原进行检测,并予以不规则抗体检测,比较最终的结果。结果:从RhE抗原检测的结果上看,RhE抗原的阳性率为51.0%(102/200),RhE抗原的阴性率为49.0%(98/200);从不规则抗体筛查的结果上看,出现不规则抗体共8例,占据比例为4.0%。其中抗-E体7例,占据比例为3.5%,其余抗体1例,占据比例为0.5%,数据对比存在明显的差异(P<0.05)。结论:在临床待输血患者中,最常出现的不规则抗体为抗-E体,而对其予以RhE抗原检测,并做好血型同型匹配输血,能够有效避免患者出现抗-E体,进一步促进临床输血的安全性。

To explore the application effect and value of RhE antigen and irregular antibody detection in patients undergoing clinical transfusion.Methods:A total of 200 patient samples were collected from several blood hospitals supervised by blood Center from February 2019 to February 2020.All patients were tested for RhE antigen by microcolumn gel method,and irregular antibody detection was performed,and the final results were compared.Results:The positive rate of RhE antigen was 51.0%(102/200)and negative rate of RhE antigen was 49.0%(98/200).According to the results of irregular antibody screening,irregular antibodies were found in 8 cases(4.0%).There were 7 cases of anti-E-body,accounting for 3.5%,and 1 case of other antibodies,accounting for 0.5%.There were significant differences between the data(P<0.05).Conclusion:In patients undergoing clinical transfusion,the most common irregular antibody is anti-E body,and RhE antigen detection and blood type matching transfusion can effectively avoid the occurrence of anti-E body in patients,and further promote the safety of clinical transfusion.