浙江省5大类食物中赭曲霉毒素A暴露评估

Ochratoxin A dietary exposure assessment in five food categories from Zhejiang Province

目的评价浙江省居民膳食赭曲霉毒素A(OTA)暴露风险。方法收集2018—2019年浙江省居民消费食物5大类24种共518份,结合浙江省2015—2016年膳食消费量调查数据,对居民OTA膳食暴露进行评估。结果OTA只在谷物及其制品中检出,而水果、茶叶、膨化食品、婴幼儿谷类辅食中均未检出OTA。燕麦及其制品OTA检出率最高为16.1%(5/31);OTA阳性样本含量范围为0.53~4.00μg/kg,其中燕麦及其制品检出含量最高,为4.00μg/kg;OTA含量均未超过我国限量标准(5μg/kg)。暴露评估显示,浙江省全人群中绝大多数消费情景下谷物及其制品膳食OTA暴露量为0.004~7.360 ng/kg BW,在OTA的安全摄入范围内(14 ng/kg BW);少数高污染高消费情景下,稻谷OTA摄入量为19.627 ng/kg BW,是安全摄入量的140.19%。不同年龄组人群以1~6岁组每日摄入量最高,为0.014~34.644 ng/kg BW,是安全摄入量的0.10%~247.46%。本研究中稻谷是浙江省居民膳食OTA的主要贡献食物,不同消费人群贡献率达到87.22%~98.32%。结论食用谷物及其制品致OTA暴露的健康风险总体较低,但少数高摄入人群存在潜在风险,特别是低年龄组消费者,需要引起关注。

Objective To evaluate the food exposure risk of ochratoxin A(OTA)in Zhejiang Province,China.Methods A representative of 518 samples(five food categories including 24 kinds of food stuffs)were examined from2018 to 2019 in order to evaluate the occurrence of OTA in Zhejiang Province.Food consumption data was collected from the Food Consumption Survey of Zhejiang Province between 2015 and 2016.Results OTA was only detected in grains and related products,but was not detected in fruits,tea,puffed foods and infant cereals.The higher incidence was found in oats and related products(16.1%,5/31);the OTA levels of positive samples ranged from 0.53 to 4.00μg/kg;and the maxium value of 4.00μg/kg was found in oats and related products;no samples exceeded the limit set by China(5μg/kg).Exposure assessment showed that in most consumption scenarios,OTA probable daily intake for eating grains and related products were 0.004-7.360 ng/kg BW,less than OTA safety exposure value of 14 ng/kg BW;the highest OTA exposure value was 19.627 ng/kg BW and represents 140.19%of the safe intake.The 1-6 years old age group had the highest daily intake of 0.014-34.644 ng/kg BW,representing 0.10%-247.46%of the safe intake.The main food source of OTA was rice with a contribution rate of 87.22%-98.32%among different scenarios.Conclusion sThe OTA intakes through grains and related products consumption by Zhejiang population do not raise safety concerns except a few high intake groups,especially young consumers.