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兰州地区空气飘尘对人淋巴细胞SCE的诱发及DNA的损伤

SISTER CHROMATID EXCHANGE AND DNA DAMAGE IN HUMAN LYMPHOCYTES INDUCED BY AIR DUST IN LANZHOU AREA
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摘要 用苯、己烷、异丙醇(7:2:1)混合溶剂萃取兰州市石油化工区及离市区西64公里农村的空气飘尘.萃取物能使人淋巴细胞姊妹染色单体互换频率(SCE)增高,使SCE比对照组增高一倍的浓度:化工区为23μg/ml、农村为47μg/ml,萃取物还能损伤DNA棋板,证明化工区空气飘尘的致突变或致癌的机率比农村大. The air dust collected from petroleum chemical industrial region in Lanzhou and rural area 64 km from the. city were extracted by mixed solvent of benzene, hexane and isopropanol (7:2:1) for 8 hours. The sister chromatid exchange (SCE) frequency was increased by all extracts and the double SCE frequency concentration of extract from air dust in the extraction system was 23 μg/ml and 47 μg/ml for samples from industrial and rural areas respectively. The extracts were found to be able to damage the DNA template as well.
出处 《环境科学学报》 CAS CSSCI CSCD 北大核心 1989年第3期352-355,共4页 Acta Scientiae Circumstantiae
基金 国家自然科学基金资助项目
关键词 淋巴细胞 SCE DNA损伤 空气飘尘 air dust DNA damage sister chromatid exchange air pollution.
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参考文献3

  • 1胡虎平,环境科学学报,1988年,2卷,232页
  • 2郑荣梁,中国科学.B,1988年,4卷,378页
  • 3赵振华,环境分析译文集.12,1981年

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