脑小血管病影像学定量评估研究进展

Recent advance in quantitative imaging evaluation of cerebral small vessel disease

脑小血管病(CSVD)是老年人群中最常见的脑血管疾病,其与缺血性脑卒中及认知功能障碍密切相关。CSVD早期的影像学评估具有重要的临床意义。目前,随着医学影像学技术的发展,CSVD早期的影像学评估逐渐从视觉分级评估发展到体积定量评估,从而更合理高效地评估CSVD的严重程度。本文现重点阐述一些影像学定量评估方法在CSVD中的应用情况,以期为CSVD的临床及基础研究提供新的评估方法和思路。

Cerebral small vessel disease(CSVD)is the most common cerebrovascular disease in the elderly,which is closely related to ischemic stroke and cognitive impairment.Early neuroimaging assessment of CSVD is of great clinical significance.With the development of medical imaging technology,it has gradually developed from visual rating assessments to quantitative volumetric assessments;therefore,it can evaluate the severity of CSVD reasonably and efficiently.This review focuses on application of some quantitative neuroimaging assessment techniques in CSVD,in order to provide new evaluation methods and ideas for clinical and basic research of CSVD.