多家血液中心献血不良反应监测工作开展情况分析

The monitoring of adverse reactions to blood donation:a multi-center analysis

目的调查多中心血液安全监测系统(HV)建立和献血不良反应(ADR)监测现状,为献血者管理提供依据。方法采用自愿填报问卷的方式调查HV运行情况,对19家血液中心2014~2018年的献血总人次数(包括机采)和其中发生的ADR例数进行数据分析。结果完成调查的24家血液中心中只有9家运行了HV,参与数据填报的19家血液中心每年发生的ADR发生率在(0.003~1.151)%,ADR例数和发生率变化趋势呈现波动状况。结论血液中心HV覆盖率尚未达到100%;ADR发生率范围跨度大,呈现波动变化趋势;利用HV加强ADR管理有待进一步提升。

Objective To investigate the establishment of multi-center haemovigilance(HV)and the monitoring of adverse reactions to blood donation(ARBD),in order to provide basis for the management of blood donors.Methods The operation of HV was investigated by questionnaire.The total number of blood donations(including plateletpheresis)and ARBD cases occurred in each blood center from 2014 to 2018 were analyzed.Results Among the 24 blood centers in this survey,only nine got HV operated.The incidence of ARBD of 19 blood centers that fulfilled the questionnaire was in the range of(0.003~1.151)%.The change trend of number and incidence of ARBD cases were indeterminate.Conclusion Most blood centers did not got HV established.The incidence of ARBD varied greatly and was indeterminate.The application of HV should be further improved to strengthen ARBD management.