成分血捐献者铁缺乏研究进展

Research progress of iron deficiency in apheresis donors

铁的消耗在全血捐献者中很常见,有大量的研究证实全血捐献者有铁缺乏的风险。随着成分献血事业的发展,成分血捐献者的健康越来越受到关注。然而,对于成分血捐献者的铁代谢情况,我们却知之甚少。近10年来,国内外对单采血浆、血小板捐献者铁营养状况进行了研究,发现捐献者铁缺乏普遍存在。目前尚无对成分献血相关铁缺乏的系统研究,本文详细梳理了成分献血相关铁缺乏的文献报道,原理机制及预防措施,以期为制定科学献血策略及保障成分血捐献者健康安全提供依据。

Objective The loss of iron stores is well documented in whole blood donors,and a large number of studies have confirmed that blood donors are at risk of iron deficiency.With the development of apheresis donation,more and more attention has been paid to the health of apheresis donors.However,little is known about the iron status of apheresis donors.In recent 10 years,iron status of apheresis donors has been studied at home and abroad,and iron deficiency was found common among them.There is no systematic study concerning apheresis donors iron deficiency at present.This article summarizes the literature,concerning the principles and preventive measures about iron deficiency in apheresis donors,and aims at improving the recruitment strategy and providing high-quality service for donors.