河北省老年人认知功能与睡眠质量关联分析

Correlation analysis of sleep quality and cognitive function in the elderly in Hebei Province

目的探讨河北省老年人认知功能与睡眠质量之间的关系。方法本研究为现况调查。通过分层、整群随机抽样纳入河北省老年人4427名,收集一般情况,评估匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI)、简易智能精神状态检查量表(mini-mental state examination,MMSE)。根据MMSE评分将老年人分为认知功能障碍组(n=2164)和认知功能正常组(n=2263)进行分析。结果认知功能障碍组和认知功能正常组间年龄、性别、婚姻状态、受教育程度、体质指数、吸烟、饮酒、睡眠质量[1.00(1.00,1.00)分vs.1.00(0.00,1.00)分]、入睡时间[1.00(1.00,3.00)分vs.1.00(0.00,3.00)分]、睡眠效率[0.00(0.00,1.00)分vs.0.00(0.00,1.00)分]、日间功能损害[0.00(0.00,0.00)分vs.0.00(0.00,0.00)分]差异具有统计学意义(P<0.05)。认知功能障碍组长睡眠(睡眠时长>9 h)者较认知功能正常组多(1.89%vs.0.93%,P=0.004)。校正混杂因素后,认知功能障碍与睡眠效率(OR=1.111)、日间功能损害(OR=1.165)、睡眠时长>9 h(以6~9 h为参照,OR=1.808)相关(P<0.05)。结论睡眠效率越差、日间功能损害越严重的老年人认知功能越差,睡眠时长>9 h较睡眠时长6~9 h的老年人认知功能差。

Objective To explore the relationship between cognitive function and sleep quality in the elderly in Hebei Province.Method This study was a cross-sectional survey.A total of 4427 elderly people in Hebei province were randomly selected by stratified and cluster sampling.General conditions were collected and Pittsburgh Sleep Quality Index(PSQI)and Mini-Mental State Examination(MMSE)were evaluated.The elderly were divided into cognitive impairment group(n=2164)and normal cognitive function group(n=2263)according to the MMSE score.Result The differences were significant in age,sex,marital status,education level,body mass index,smoking,alcohol consumption,sleep quality[1.00(1.00,1.00)points vs.1.00(0.00,1.00)points],time to sleep[1.00(1.00,1.00),0.00)points vs.1.00(0.00,3.00)points],sleep efficiency[0.00(0.00,1.00)points vs.0.00(0.00,1.00)points],daytime functional impairment[0.00(0.00,1.00)points vs.0.00(0.00,0.00)points]between cognitive impairment group and normal group(P<0.05).Long sleep(sleep duration>9 h)was more common in the cognitive impairment group than in the normal group(1.89%vs.0.93%,P=0.004).After adjusting for confounding factors,cognitive impairment was correlated with sleep efficiency(OR=1.111),daytime functional impairment(OR=1.165)and sleep duration(P<0.05).Conclusion The elder people with worse sleep efficiency and more serious daytime functional impairment have worse cognitive function,and the elder people with sleep duration>9 h have worse cognitive function than those with sleep duration 6-9 h.