盐酸多柔比星脂质体致急性喉头水肿1例的护理体会

Nursing Experience of One Case of Acute Laryngeal Edema Caused by Doxorubicin Hydrochloride Liposome

1例老年男性患者因确诊外周T细胞淋巴瘤给予DA-EPOCH方案化疗,输注盐酸多柔比星脂质体后出现面部麻木、喉部发紧、颈部不适,伴有呼吸困难、舌部肿大、声音嘶哑、口齿不清等症状,查体见舌体肥大,颈部肿胀、增粗,遵医嘱予注射用甲泼尼龙琥珀酸钠、地塞米松静脉注射、10%葡萄糖酸钙静脉滴注,同时给予心电监护、氧气吸入,床边备中心负压吸引装置、气管插管导管、气管切开包,约2h后患者症状逐渐好转,生命体征平稳。疾病过程中护士及时发现患者并发症发生情况,配合医生给予对症治疗,密切观察患者病情变化,后患者安全化疗结束并出院。

An elderly male patient admitted to our hospital was diagnosed with peripheral T-cell lymphoma,and was treated with DA-EPOCH chemotherapy.During chemotherapy,facial numbness,gasping and neck discomfort,was accompanied by dyspnea,tongue swelling,hoarseness,and slurred speech when the patient was infused with doxorubicin hydrochloride liposome.Physical examination revealed hypertrophy of the tongue and swelling and thickening of the neck.The patient was given intravenous injection of methylprednisolone sodium succinate and dexamethasone,intravenous infusion of 10%calcium gluconate.At the same time,ECG monitoring,oxygen inhalation was given,and the central negative pressure suction device,endotracheal tube and tracheotomy packs were prepared at the bedside.About two hours later,the patient's symptoms gradually relieved and his vital signs were stable.In the course of this complication,the nurse observed the occurrence of complications in time,cooperated with the doctors to give emergency rescue,and further strengthened the inspection and monitoring of patients.The patient finally completed the chemotherapy uneventfully and was discharged after chemotherapy.