血浆铁蛋白和血清Mg、Fe、Zn、Ca水平与儿童反复呼吸道感染病情严重程度的关系研究

Relationship between plasma ferritin and serum Mg,Fe,Zn,Ca levels and the severity of recurrent respiratory infections in children

目的探讨血浆铁蛋白和血清镁(Mg)、血清铁(Fe)、血清锌(Zn)、血清钙(Ca)水平与儿童反复呼吸道感染病情严重程度的关系。方法选取2017年6月至2018年12月收入医院的反复呼吸道感染儿童102例。根据疾病严重程度将轻度患儿分为A组(41例),将中度患儿分为B组(34例),将重度患儿分为C组(27例),观察并分析三组患儿与血浆铁蛋白和血清微量元素水平的关系。结果随着病情程度愈渐加重,患儿血浆铁蛋白和血清Mg、Fe、Zn、Ca水平均明显降低(P<0.05)。经Spearman相关分析得到,反复呼吸道感染病情严重程度与血浆铁蛋白和血清Mg、Fe、Zn、Ca水平均呈明显负相关。结论血浆铁蛋白和血清Mg、Fe、Zn、Ca水平越低,儿童反复呼吸道感染病情越重,故应重视儿童微量元素的缺乏并严密监测血浆铁蛋白水平,以防止或预测疾病的发生。

Objective To investigate the relationship between the levels of plasma ferritin,serum magnesium(Mg),serum iron(Fe),serum zinc(Zn),serum calcium(Ca)and the severity of recurrent respiratory infections in children.Methods A total of 102 children with recurrent respiratory infections admitted to the hospital from June 2017 to December 2018 were selected.According to the severity of the disease,mild patients were assigned to group A(41 cases),moderate patients were assigned to group B(34 cases),and severe patients were assigned to group C(27 cases).The relationship between the severity and the levels of plasma ferritin and serum trace elements was analyzed.Results As the severity of the disease got worse,plasma ferritin and serum Mg,Fe,Zn,and Ca levels decreased significantly(P<0.05).Spearman correlation analysis showed that the severity of recurrent respiratory infections was significantly negatively correlated with plasma ferritin and serum Mg,Fe,Zn,and Ca levels.Conclusion The lower the levels of plasma ferritin and serum Mg,Fe,Zn,Ca,the more severe the recurrent respiratory infections.Therefore,attention should be paid to the lack of trace elements in children and the level of plasma ferritin should be closely monitored to prevent or predict the occurrence of diseases.