基于事件相关电位评估重复性亚脑震荡拳击运动员的反应抑制功能

Response inhibitory function of boxers with repetitive subconcussions based on event-related potentials

目的在Go/Nogo实验范式下应用事件相关电位(ERP)评估重复性亚脑震荡拳击运动员的反应抑制功能。方法选择29例来自武汉体育学院的拳击运动员纳入亚脑震荡组,28例来自武汉晴川学院的大学生纳入健康对照组。采用64导联电极弹性帽记录头皮脑电数据的同时完成可视化的Go/Nogo实验范式。E-prime2.0软件记录行为学数据。提取脑电数据中ERP成分,对两组ERP中P3成分的振幅、潜伏期进行重复测量方差分析,对Nogo-N2成分和行为学数据进行两独立样本T检验。结果在Go刺激下亚脑震荡组P3平均振幅低于健康对照组[(6.327±0.497)μV比(8.007±0.505)μV,F=5.622,P<0.05],Nogo刺激下亚脑震荡组P3平均振幅低于健康对照组[(6.741±0.559)μV比(9.962±0.569)μV,F=16.297,P<0.01];在Nogo刺激下亚脑震荡组N2潜伏期时间长于健康对照组[(275.714±50.943)ms比(252.571±33.201)ms,t=-2.014,P<0.05]。行为学表现中,Go刺激下亚脑震荡组正确率低于健康对照组[(97.3±1.9)%比(98.3±1.1)%,t=-2.476,P<0.05];Nogo刺激下亚脑震荡组正确率低于健康对照组[(90.0±6.6)%比(92.8±3.3)%,t=-2.036,P<0.05]。结论重复性亚脑震荡拳击运动员可能存在与冲突检测和反应抑制相关的认知功能障碍。

Objective To evaluate the response inhibitory function of boxers with repetitive subconcussions using event-related potentials(ERPs)in the Go/Nogo paradigm.Methods Totally,29 boxers from Wuhan Physical Education Institute were enrolled in subconcussion group,and 28 college students from Wuhan Qingchuan University served as healthy control group.A 64-channel electrode elastic cap was used to record continuous scalp EEG data while completing the visual Go/Nogo experimental paradigm.E-Prime 2.0 software was used to record behavioral data.ERP components were extracted from EEG data,and the amplitude and latency of P3 component in ERP of the two groups were analyzed by repeated measure ANOVA.Two independent sample T tests were performed for Nogo-N2 component and behavioral data.Results In ERP results,the mean amplitude of P3 in subconcussion group was lower than that in healthy control group under Go stimulation[(6.327±0.497)μV vs.(8.007±0.505)μV,F=5.622,P<0.05],the mean amplitude of P3 in subconcussion group was lower than that in healthy control group under Nogo stimulation[(6.741±0.559)μV vs.(9.962±0.569)μV,F=16.297,P<0.01],the latency of N2 in the subconcussion group was longer than that in the healthy control group under Nogo stimulation[(275.714±50.943)ms vs.(252.571±33.201)ms,t=-2.014,P<0.05].In behavioral performance,the accuracy rate of subconcussion group was lower than that of healthy control group under Go stimulation[(97.3±1.9)%vs.(98.3±1.1)%,t=-2.476,P<0.05],and the accuracy rate of subconcussion group was lower than that of healthy control group under Nogo stimulation[(90.0±6.6)%vs.(92.8±3.3)%,t=-2.036,P<0.05].Conclusion These results preliminarily reveal that boxers with repetitive subconcussion may have cognitive impairments related to conflict detection and response inhibitory.