脓毒症心肌病——从发病机制到临床管理

Septic cardiomyopathy:from pathogenesis to clinical management

脓毒症心肌病(SCM)是一种继发于脓毒症的急性心功能不全的综合征,其发病率高,并能显著增加脓毒症患者病死率。SCM临床表现缺乏特异性,其发病机制尚未明确,临床治疗缺乏统一标准,其死亡率较高,临床上对其认识不足。本文结合近年来研究,探讨SCM定义、发病机制、病理生理学及临床管理,为临床更好理解SCM病程,优化治疗策略提供参考。

Septic cardiomyopathy(SCM)is a syndrome of acute cardiac insufficiency secondary to sepsis,which has a high incidence and can significantly increase the mortality of patients with sepsis.The clinical manifestations of SCM are not specific,its pathogenesis is not clear,and there is no unified standard for clinical treatment.However,the mortality rate of SCM is high,and clinical understanding of SCM is insufficient.In this paper,based on recent studies,the definition,pathogenesis,pathophysiology and clinical management of SCM were discussed,so as to provide reference for better understanding of SCM disease course and optimization of therapeutic strategies.