摘要
应激性高血糖属于机体自我保护机制,在应激状态下可引起非特异性适应性的血糖变化,常见于急性心肌梗死等疾病中。近年来多项研究发现,应激性高血糖可促使急性心肌梗死病情的恶化,对其病情严重程度及患者预后结局均具有不良影响,其作用机制可涉及氧化应激反应、凝血及抗凝系统失衡、血管内皮功能障碍及无复流等。基于此,本文结合急性心肌梗死患者应激性高血糖的发生机制及损伤原理,对其研究进展作一综述,以供临床参考。
Stress hyperglycemia belongs to the body's self-protection mechanism,which can cause non-specific adaptive changes in blood glucose under stress,and is common in acute myocardial infarction and other diseases.In recent years,a number of studies have found that stress hyperglycemia can promote the deterioration of acute myocardial infarction,which has adverse effects on the severity of the disease and the prognosis of patients.Its mechanism can be related to oxidative stress response,imbalance of coagulation and anticoagulation system,vascular endothelial dysfunction and no-reflow.Based on this,this paper reviews the research progress of stress hyperglycemia in patients with acute myocardial infarction in combination with the mechanism and damage principle of stress hyperglycemia,so as to provide clinical reference.
作者
何丽
HE Li(Department of Physical Examination,Tianjin Occupational Diseases Precaution and Therapeutic Hospital,Tianjin 300011,China)
出处
《医学信息》
2022年第10期74-77,共4页
Journal of Medical Information
关键词
应激性高血糖
急性心肌梗死
氧化应激
胰岛素抵抗
无复流
Stress hyperglycemia
Acute myocardial infarction
Oxidative stress
Insulin resistance
No reflow
