臭氧联合PRP治疗中老年人膝关节炎临床疗效

Clinical efficacy of ozone therapycombined with platelet rich plasma in treatment of middle-aged and elderly patients with knee osteoarthritis

目的通过与单独使用臭氧疗法的对比探讨出臭氧联合PRP治疗中老年人膝关节炎的临床疗效。方法回顾性分析2021年1月—2021年6月,济宁市第二人民医院输血科联合疼痛科收治40例符合纳入条件的患者。根据不同的治疗方法,把跟踪研究的病号分为两组即实验组和对照组各20例。对照组进行关节腔注射臭氧10~30 mL的25~30μg/m LK医用臭氧,实验组在此基础上于术中予以关节腔内注射富血小板血浆4~5 mL。经过对比两组治疗前及治疗后一个月、三个月、半年的各项评分标准,进而最终确定两组的疗效。结果观察组在治疗后3个时间点的随访过程中VAS评分、WOMAC指数总体上均低于对照组,且P<0.05具有统计学意义。结论臭氧疗法联合PRP治疗比单独使用臭氧效果更佳加强了单独使用臭氧疗法对疼痛和运动功能的改善且安全有效。

Objective Comparing with simple ozone therapy in the treatment of knee osteoarthritis to observe the clinical efficacy of ozone therapy combined with intra-articular injection of platelet rich plasma(PRP).Methods From January 2021 to June 2021,totally 40 eligible patients were retrospectively analyzed.According to different treatment methods,divided into two groups which were treatment and control,each group has 20 cases.The control group was given ozone therapy,and the treatment group was given intra-articular injection of 4-5 mL platelet rich plasma on this basis.The curative effect of the two groups was finally determined by comparing the scores of the two groups before treatment and 1 month,3 months and half a year after treatment.Results The VAS score and WOMAC index of the control group were higher than those of the treatment group in the three stages of follow-up after treatment,and the difference was statistically significant(P<0.05).Conclusion The effect of ozone therapy combined with platelet rich plasma in the treatment of knee osteoarthritis is better than simple ozone therapy,can relieve knee pain and improve joint function better,and also safely and effectively.