原发性骨质疏松症患者热敏灸疗临床疗效及对患者睾酮、骨化三醇水平的影响

Clinical Effect of Thermal Moxibustion on Patients with Primary Osteoporosis and Its Effect on Testosterone and Calcitriol Levels

目的探讨原发性骨质疏松症患者热敏灸治疗的临床疗效及对患者睾酮、骨化三醇水平的影响。方法选取该院在2017年8月—2018年8月期间进行检查治疗的骨质疏松患者82例,应用随机数字表法将患者分为对照组与研究组。对照组给予患者口服碳酸钙D_(3)片治疗,研究组在对照组的基础上于大杼、脾俞、肾俞、中脘、关元、足三里穴区探寻热敏腧穴行热敏灸治疗,每周3次,两组均6周为1个疗程。比较两组患者治疗前后睾酮以及骨化三醇水平,生活质量以及骨密度,疼痛感评分。结果治疗后临床总有效率研究组为95.1%高于对照组的75.6%(P<0.05);治疗前两组患者的睾酮以及血浆骨化三醇含量指标对比不具统计学意义(P>0.05),治疗后研究组的睾酮以及血浆骨化三醇水平明显高于对照组(P<0.05);治疗前两组患者的生活质量评分差异无统计学意义,治疗后研究组社会、躯体以及角色、认知等功能明显提高,研究组生活质量评分高于对照组(P<0.05);两组患者治疗前骨密度及疼痛感评分差异无统计学意义,治疗后,研究组较对照组患者的疼痛感评分明显降低且骨密度值明显升高(P<0.05)。结论热敏灸治疗原发性骨质疏松症疗效确切,明显提高患者的睾酮以及骨化三醇水平,生活质量明显提高,降低了患者的疼痛感评分,对患者的骨密度值改善较大,值得推广应用。

Objective To explore the clinical effect of thermal moxibustion on patients with primary osteoporosis and its influence on testosterone and calcitriol levels.Methods 82 patients with osteoporosis who were examined and treated in our hospital from August,2017 to August,2018 were divided into control group and study group by random number list method.Patients in the control group were treated with calcium carbonate D_(3) tablets orally,while those in the study group were treated with heat-sensitive moxibustion in Dazhu(BL11),Pishu(BL20),Shenshu(BL23),Zhongwan(RN12),Guanyuan(RN14)and Zusanli(ST36)acupoints on the basis of the control group,three times a week,with 6 weeks as a course of treatment.The levels of testosterone and calcitriol,quality of life,bone density and pain scores were compared between the two groups before and after treatment.Results The effective rate of the study group was 95.1% higherthan that of the control group(75.6%,P<0.05).Before treatment,there was no significant difference in the levels of testosterone and calcitriol between the two groups before and after treatment(P>0.05),but the levels of testosterone and calcitriol in the study group were significantly higher than those in the control group(P<0.05).There was no significant change in the quality of life scores in the two groups before treatment.The social,physical,role and cognitive functions in the study group were significantly improved after treatment,and the quality of life scores in the study group were higher than those in the control group(P<0.05).Before treatment,there was no significant difference in bone mineral density and bone mineral density score between the two groups.After treatment,the bone mineral density score of the study group was significantly lower than that of the control group(P<0.05).Conclusion Heat-sensitive moxibustion is effective in the treatment of primary osteoporosis,which obviously improves the testosterone and calcitriol levels of patients,improves the quality of life,reduces the pain score of patients,and greatly improves the bone mineral density of patients,which is worthy of popularization and application.