磁共振影像生物标志物预测肝细胞癌术后复发风险的研究进展

Research progress on magnetic resonance imaging biomarkers in predicting the risk of postoperative recurrence with hepatocellular carcinoma

MRI可以预测肝细胞癌的预后,近年来功能MRI和肝胆特异性对比剂的应用推广以及影像组学的发展,使得MRI预测肝细胞癌预后及复发风险评估这一研究领域进一步深化,并探索出部分影像生物标志物。本文对此类磁共振影像生物标志物的定义、特征、潜在发生机制及临床关联进行综述,旨在提高对MRI评估肝细胞癌术后复发价值的认识,更好地辅助科研和指导临床实践。

Magnetic resonance imaging can predict prognosis of hepatocellular carcinoma.In recent years,the application and promotion of functional magnetic resonance imaging and hepatobiliary specific contrast agents as well as the development of imaging omics have further deepened the research field of prediction of prognosis and recurrence risk assessment of hepatocellular carcinoma by magnetic resonance imaging.Besides,some imaging biomarkers have been explored.In this paper,the definition,characteristics,potential mechanisms and clinical relevance of magnetic resonance imaging biomarkers were reviewed.It aims to improve the understanding of the evaluation value of postoperative recurrence of hepatocellular carcinoma by magnetic resonance imaging,and to better assist scientific research and guide clinical practice.