Mechanism of Hezhong Jiangzhuo Tiaotang granule in treating obesity type 2 diabetes mellitus with syndrome of phlegm-dampness based on the microbiota 16S rDNA sequencing

Objective To investigate the mechanism of Hezhong Jiangzhuo Tiaotang Granule(HZJZTTG)in treating type 2 diabetes(T2 DM)with syndrome of phlegm-dampness.Methods Totally 66 cases of obese T2 DM patients(syndrome of phlegmdampncss)from the Department of Endocrinology,Kaifeng Traditional Chinese Medicine Hospital were recruited.According to random number table,the patients were assigned to treatment group treated with HZJZTTG,and control group treated with metformin hydrochloride Tablets,33 cases in each group and the course of treatment was 12 weeks.