Hippo-YAP信号通路与心血管系统的研究进展

Research progress of Hippo-YAP signaling pathway and cardiovascular system

Hippo-YAP信号通路是目前十分热门的一个研究项目,不仅因其能够调控细胞增殖、凋亡,而且它和其他信号通路之间也有很大的联系。目前研究认为该通路在心血管系统发育、再生、细胞凋亡及心血管疾病等方面有着举足轻重的作用,深入研究Hippo-YAP信号通路的作用机制不仅可以为人们了解心血管疾病提供更多的理论基础,还可能为心血管疾病的预防和靶向治疗带来新的思路。

The Hippo-YAP signaling pathway is currently a very popular research project,not only because it can regulate cell proliferation and apoptosis,but also because it has a great relationship with other signaling pathways.Current research consider that this pathway plays a pivotal role in cardiovascular system development,regeneration,apoptosis,and cardiovascular diseases.In-depth study of the mechanism of Hippo-YAP signaling pathway can not only provide more theoretical basis for people to understand cardiovascular diseases,but also may bring new ideas for the prevention and targeted therapy of cardiovascular diseases.