腹腔镜子宫切除术对子宫肌瘤患者疗效及血清性激素水平分析

Analysis of Curative Effect of Laparoscopic Hysterectomy on Patients with Uterine Fibroids and Serum Sex Hormone Levels

目的研究子宫肌瘤患者行腹腔镜子宫切除术的效果及对其血清性激素水平的影响。方法回顾性分析该院2016年1月—2019年12月收治的100例子宫肌瘤行子宫切除术患者资料,根据手术方式不同分为对照组(n=48)、研究组(n=52),对照组采取经腹切除术,研究组采取腹腔镜下切除术。比较两组手术指标、并发症及血清性激素水平情况。结果研究组手术时间(144.53±14.28)min长于对照组,差异有统计学意义(t=10.069,P<0.05),术中出血量(84.27±25.41)mL、排气时间(20.62±2.96)h、下床时间(20.25±1.74)h、住院时间(7.31±1.25)d,均优于对照组,差异有统计学意义(t=12.870、18.170、53.815、6.805,P<0.05);研究组并发症发生率8.33%低于对照组的11.52%,但差异无统计学意义(χ^(2)=0.040,P>0.05)。研究组T2时刻P(1.01±0.35)mmol/mL、E_(2)(96.31±6.79)pg/mL、FSH(12.37±1.15)U/L、LH(13.84±1.94)U/L优于对照组,差异有统计学意义(t=7.659、7.365、3.914、3.265,P<0.05)。结论腹腔镜全子宫+输卵管切除术相较于常规开腹手术对于患者造成的损伤更少,同时对其血清性激素水平的影响更小,有利于患者术后恢复和疾病预后。

Objective To study the effect of laparoscopic hysterectomy in patients with uterine fibroids and its influence on serum sex hormone levels.Methods A retrospective analysis of the data of 100 patients with uterine fibroids who underwent hysterectomy in the hospital from January 2016 to December 2019.According to different surgical methods,they were divided into control group(n=48)and study group(n=52).The control group underwent transabdominal resection,and the study group underwent laparoscopic resection.The surgical indicators,complications and serum sex hormone levels were compared between the two groups.Results The operation time of the study group was(144.53±14.28)min longer than that of the control group,and the difference was statistically significant(t=10.069,P<0.05).Intraoperative blood loss(84.27±25.41)mL,exhaust time(20.62±2.96)h,bed time(20.25±1.74)h,hospitalization time(7.31±1.25)d,all better than the control group,and the difference was statistically significant(t=12.870,18.170,53.815,6.805,P<0.05).The complication rate of 8.33%in the study group was lower than 11.52%in the control group,but the difference was not statistically significant(χ^(2)=0.040,P>0.05).At T2,P(1.01±0.35)mmol/mL,E_(2)(96.31±6.79)pg/mL,FSH(12.37±1.15)U/L,LH(13.84±1.94)U/L of the study group were better than those of the control group,and the difference was statistically significant(t=7.659,7.365,3.914,3.265,P<0.05).Conclusion Laparoscopic total hysterectomy+salpingectomy causes less damage to patients than conventional open surgery.At the same time,the effect on serum sex hormone levels is smaller,which is beneficial to patients'postoperative recovery and disease prognosis.