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老年高血压脑出血患者皮质脊髓束损坏程度对认知功能的影响 被引量:8

Effects of corticospinal tract damage on cognitive function in elderly patients with hypertensive intracerebral hemorrhage
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摘要 目的探讨老年高血压脑出血(HICH)患者皮质脊髓束(CST)损坏程度对认知功能的影响。方法收集57例保守治疗HICH患者,应用弥散张量成像(DTI)技术测量入院时及入院21 d大脑脚及内囊的各向异性分数(FA),并进行入院时CST分级,根据CST分级,分为保守治疗1组和保守治疗2组,于出血6个月后采用重复性成套神经心理状态测验量表(RBANS)评估患者认知功能。结果保守治疗2组即刻记忆评分显著低于保守治疗1组(均P<0.05)。HICH患者入院21 d患侧CST的FA均值与即刻记忆、延迟记忆评分及标准分呈正相关(均P<0.05)。多元线性回归分析,HICH患者入院21 d时患侧CST的FA值与6个月后即刻记忆评分、标准分仍显著相关(P<0.05)。结论HICH患者入院21 d患侧CST的FA值越低,CST损坏越严重,6个月后认知功能越差。
作者 刘兴宇 张晓飞 田宝刚 洪军 王凯杰 王余 崔建忠 LIU Xing-Yu;ZHANG Xiao-Fei;TIAN Bao-Gang
出处 《中国老年学杂志》 CAS 北大核心 2022年第7期1557-1560,共4页 Chinese Journal of Gerontology
基金 河北省科技计划项目(162777156)。
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