临床微生物检验中细菌耐药性监测的应用分析

Application Analysis of Bacterial Drug Resistance Monitoring in Clinical Microbiological Examination

目的针对临床微生物检验中细菌耐药性监测的应用效果进行研究。方法选择2020年1月—2021年1月期间在该院收集到的118株非重复性病原菌检测样本,对其耐药性情况加以检测分析。结果铜绿假单胞菌与大肠埃希菌、肺炎克雷伯菌3种病原菌相比,铜绿假单胞菌对头孢呋辛的耐药性(100.00%)、头孢噻肟的耐药性(94.12%)、亚胺培南的耐药性(35.29%)、美罗培南的耐药性(29.41%)、氨曲南的耐药性(88.24%)、哌拉西林舒巴坦的耐药性(17.65%)在3种病原菌中最高。大肠埃希菌与铜绿假单胞菌、肺炎克雷伯菌相比,对头孢吡肟的耐药性(26.32%)、对环丙沙星的耐药性(73.68%)、阿米卡星的耐药性(21.05%)在3种病原菌中最高。结论在临床微生物检验中,进行细菌耐药性监测十分重要,有利于增加细菌检出率,推动临床用药治疗安全性的增强。

Objective The application effect of bacterial resistance monitoring in clinical microbiological testing was studied.Methods The detection samples of 118 non-repetitive pathogenic bacteria collected in the hospital from January 2020 to January 2021 were selected,and their drug resistance was detected and analyzed.Results Compared with Escherichia coli and Klebsiella pneumoniae,Pseudomonas aeruginosa was resistant to cefuroxime(100.00%),cefotaxime(94.12%),imipenem(35.29%),meropenem(29.41%),aztreonam(88.24%),piperacillin sulbactam(17.65%)was the highest among the 3 pathogens.Compared with Pseudomonas aeruginosa and Klebsiella pneumoniae,Escherichia coli was resistant to cefepime(26.32%),ciprofloxacin(73.68%),amikacin(21.05%)was the highest among the three pathogens.Conclusion In clinical microbiology testing,it is very important to monitor bacterial resistance,which is beneficial to increase the detection rate of bacteria and promote the safety of clinical drug treatment.