二甲硅油服用时间在胶囊内镜肠道清洁中的效果比较

Comparison of the Effect of Simethicone Taking Time in Capsule Endoscopy Bowel Cleansing

目的研究不同的二甲硅油服用时间对胶囊内镜肠道清洁的效果。方法选择2017年8月—2020年8月期间该院收治的60例消化道疾病患者为研究对象,将随机数表法作为分组原则,随机分为3组,分别为A组(n=20)、B组(n=20)、C组(n=20),A组患者在服用洗肠液后立刻口服二甲硅油散;B组患者在肠镜检查前1 h口服二甲硅油散;C组患者在肠道准备干净后1 h口服二甲硅油散,比较3组患者肠道清洁程度评分(左半结肠、横结肠、右半结肠);肠道气泡程度评级(左半结肠、横结肠、右半结肠);不良反应评级;肠镜检查到达回盲部所用时间;耐受度。结果A组、B组、C组患者左半结肠、横结肠、右半结肠的肠道清洁程度评分比较,差异无统计学意义(P>0.05);B组患者左半结肠、横结肠、右半结肠气泡程度评级均低于A组、C组患者,A组患者左半结肠、横结肠、右半结肠的气泡程度评级均低于C组患者,3组比较差异有统计学意义(P<0.05);A组、B组、C组患者不良反应分级比较差异无统计学意义(P>0.05);A组患者肠镜检查到达回盲部所用时间为(9.09±3.91)min,B组患者肠镜检查到达回盲部所用时间为(7.02±3.12)min,C组患者肠镜检查到达回盲部所用时间为(12.52±4.39)min,3组比较差异有统计学意义(F=10.453,P<0.05);A组、B组、C组患者耐受度比较差异无统计学意义(P>0.05)。结论胶囊内镜肠道清洁过程中,二甲硅油服用时间不同,会对患者的肠道气泡程度评级以及肠镜检查到达回盲部所用时间造成影响,在肠镜检查前1 h口服二甲硅油散是最有利于肠道清洁的,临床中应该尽可能保证在肠镜检查前1 h口服二甲硅油散。

Objective To study the effect of different administration time of simethicone on intestinal cleaning by capsule endoscopy.Methods 60 patients with digestive tract diseases admitted to the hospital from August 2017 to August 2020 were selected as the study objects,used the random number table method as the grouping principle,they were randomly divided into 3 groups,namely group A(n=20),group B(n=20),group C(n=20),patients in group A took simethicone powder orally immediately after taking colon wash;patients in group B took simethicone powder orally 1 h before colonoscopy;patients in group C took simethicone powder 1 h after bowel preparation.The scores of intestinal cleanliness(left colon,transverse colon,and right colon)and the degree of intestinal air bubbles(left colon,transverse colon,and right colon),adverse reaction rating;time taken for colonoscopy to reach the ileocecal area;tolerance were compared among the three groups.Results There was no statistically significant difference in the scores of intestinal cleanliness between groups A,B and C in the left colon,transverse colon and right colon(P>0.05).The bubble degree ratings of the left colon,transverse colon,and right colon in group B were lower than those in groups A and C,and the bubble degree ratings in the left colon,transverse colon,and right colon of group A were lower than those in group C.Three groups were compared the difference was statistically significant(P<0.05).Comparison of adverse reaction grades in group A,group B and group C,the difference was not statistically significant(P>0.05).The time it took for the colonoscopy to reach the ileocecum in group A was(9.09±3.91)min,the time for colonoscopy in group B to reach the ileocecal was(7.02±3.12)min,the colonoscopy for group C the time it took to check to the ileocecal area was(12.52±4.39)min,the difference was statistically significant(F=10.453,P<0.05).The tolerance of patients in group A,group B and group C was compared,the difference was not statistically significant(P>0.05).Conclusion During the bowel cleaning process of capsule endoscopy,the different time of taking simethicone will affect the degree of intestinal air bubbles and the time it takes for the colonoscopy to reach the ileocecal area.When taking simethicone powder orally 1 h before colonoscopy,it is most beneficial to intestinal cleaning.In clinical practice,it should be ensured that simethicone powder is taken orally 1 h before colonoscopy.