^(18)F-FDG PET-CT模拟定位在复发腹盆腔肿瘤放疗中的应用

Application of ^(18)F-FDG PET-CT Simulation Localization in Radiotherapy of Recurrent Abdominal and Pelvic Tumors

目的探讨^(18)F-FDG PET-CT模拟定位在复发腹盆腔肿瘤放疗中的临床价值。方法采用^(18)F-FDG PET-CT对38例治疗后复发的腹盆腔肿瘤患者进行模拟定位,分别根据CT影像及^(18)F-FDG PET-CT拟定全身治疗方案及放疗靶区勾画,对比二者差异。结果在38例患者中,21.1%(8/38)发现了盆腹腔外远处转移,改变了治疗方案。34例(89.5%)放射治疗靶区发生了改变。GTV_(PET-CT)的均值为118.14 cm^(3),GTV_(CT)的均值为148.53 cm^(3)(P=0.044)。结论^(18)F-FDG PET-CT模拟定位对于复发盆腹腔肿瘤患者,完善了肿瘤再分期,改变了部分患者治疗方案,更加精确放射治疗靶区。

Objective To investigate the clinical application value of ^(18)F-FDG PET-CT simulation localization in radiotherapy of recurrent abdominal and pelvic tumors.Methods ^(18)F-FDG PET-CT was used to simulate positioning 38 patients with abdominal and pelvic tumors who relapsed after treatment.Based on both CT images and ^(18)F-FDG PRT-CT,we drew up a systemic treatment plan and outlined the radiotherapy target area,and then compared the differences between the two methods.Results In 38 patients,21.1%(3/8)of patients were found to have distal metastases outside the pelvic and abdominal cavity,and changed the systemic treatment plan.The radiotherapy target was altered in 34(89.5%)patients.The mean value of GTV_(PET-CT) was 118.14cm3 and the mean value of GTV_(CT) was 148.53cm3(P=0.044).Conclusion For patients with recurrent abdominal and pelvic tumors,^(18)F-FDG PET-CT simulation localization treatment improves tumor re-staging,changes the integrated therapy for some patients,and makes the target area of radiotherapy more accurate.