六味地黄丸联合二甲双胍治疗2型糖尿病临床疗效研究

Study on the Clinical Efficacy of Liuwei Dihuang Pills Combined with Metformin in the Treatment of Type 2 Diabetes

目的探究六味地黄丸联合二甲双胍治疗2型糖尿病的临床疗效。方法选取2018年4月—2020年7月该院收治的94例2型糖尿病患者为研究对象,随机数表法分为对照组(行二甲双胍治疗)与观察组(行六味地黄丸联合二甲双胍治疗)。比较两组治疗效果。结果治疗前,两组血糖、血脂水平对比,差异无统计学意义(P>0.05);治疗后,观察组血糖值低于对照组,差异有统计学意义(P<0.05)。观察组高密度脂蛋白胆固醇(HDL-C)高于对照组,总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)低于对照组,差异有统计学意义(P<0.05)。观察组治疗有效率93.62%高于对照组76.60%,差异有统计学意义(P<0.05)。结论六味地黄丸联合二甲双胍应用2型糖尿病中可改善患者的血糖、血脂水平,治疗效果显著。

Objective To explore the clinical efficacy of Liuwei Dihuang Pills combined with metformin in the treatment of type 2 diabetes.Methods From April 2018 to July 2020,94 patients with type 2 diabetes in thehospital were selected as the subjects.The random number table method was divided into the control group(metformin treatment)and the observation group(Liuwei Dihuang pill combined with metformin).The therapeutic effects of the two groups were compared.Results Before treatment,there was no significant difference in blood glucose and blood lipid levels between the two groups(P>0.05).After treatment,the blood glucose level of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).The high-density lipoprotein cholesterol(HDL-C)in the observation group was higher than that in the control group,and the total cholesterol(TC),triacylglycerol(TG),and low-density lipoprotein cholesterol(LDL-C)were lower than those in the control group,and the differences was statistically significant(P<0.05).The effective rate of treatment in the observation group was 93.62%higher than that in the control group 76.60%,and the difference was statistically significant(P<0.05).Conclusion Liuwei Dihuang pills combined with metformin in type 2 diabetes can improve blood glucose and blood lipid,has a significant therapeutic effect.