基于喷雾干燥法制备微胶囊作为生物活性成分递送体系的研究进展

Research Progress of Microcapsule Delivery System Based on Spray Drying Method to Improve the Availability of Bioactive Ingredients

食品和饮料工业经常需要在产品中包封疏水功能成分,包括色素、香料、脂质和维生素。胶囊化可以改善这些功能性成分的可操作性、水分散性、化学稳定性和释放效果。文中重点介绍了基于喷雾干燥的微胶囊递送体系的设计,以包封、保护和传递生物活性成分;强调了喷雾干燥制备微胶囊经历的过程;讨论了壁材选择对微胶囊的影响,重点阐述了蛋白型、多糖型及复合型微胶囊壁材的研究情况;列举了喷雾干燥制备微胶囊递送体系在提高各种生物活性成分的生物利用度方面的应用实例。

The food and beverage industry often needs to encapsulate hydrophobic functional ingredients in its products,including pigments,spices,lipids,health preservatives and vitamins.Encapsulation can improve the maneuverability,water dispersibility,chemical stability and release effect of these functional components.In this paper,the design of microcapsule delivery system based on spray drying to encapsulate,protect and deliver bioactive components was introduced.The process of preparing microcapsules by spray drying was emphasized.The influence of wall material selection on microcapsules was discussed,with emphasis on the research of protein type,polysaccharide type and composite microcapsule wall materials.The application examples of spray drying microcapsule delivery system in improving the bioavailability of various bioactive components(β-carotene,curcumin and coenzyme Q10) were enumerated.This paper in order to provide reference for the application of spray drying in functional food.