DTI纤维束重建联合术中超声在脑功能区胶质瘤手术中的应用

Application of DTI Fiber Bundle Reconstruction Combined with Intraoperative Ultrasound in Glioma Surgery of Brain Functional Areas

本文目的是探讨弥散张量成像(DTI)纤维束重建联合术中超声在脑功能区胶质瘤手术中的应用价值,选取脑功能区胶质瘤患者89例,其中观察组(n=46)给予DTI纤维束重建联合术中超声,对照组(n=43)给予术中超声定位,两组均给予脑胶质瘤切除术,结果显示:观察组肿瘤全切率、术后Karnofsky功能状态(KPS)评分、症状好转比例、Anderson脑肿瘤症状评估量表(MDASI-BT)评分优于对照组(P<0.05)。观察组治疗无变化或加重患者病理类型高级别比例、各向异性分数(FA)值高于好转患者(P<0.05),表观扩散系数(ADC)值低于好转患者(P<0.05);FA值、ADC值预测观察组患者治疗好转的ROC曲线下面积分别为0.756和0.803,P<0.05。脑功能区胶质瘤手术应用DTI纤维束重建联合术中超声有较好的使用价值,值得临床使用。

This paper investigated the value of diffusion tensor imaging(DTI)fiber bundle reconstruction combined with intraoperative ultrasound in the operation of gliomas in brain functional areas.89 patients with gliomas in brain functional areas were selected,the observation group(n=46)was given DTI fiber bundle reconstruction combined with intraoperative ultrasound,and the control group was given intraoperative ultrasound localization,and both groups were given glioma resection surgery.The results showed that the total tumor resection rate,postoperative Karnofsky functional state(KPS)score,the proportion of symptom improvement,the score of Anderson brain tumor symptom assessment scale(MDASI-BT)in the observation group were better than those in the control group(P<0.05).In the observation group,the high-level proportion and anisotropy score(FA)of pathological types in patients with no change or aggravation were higher than those in improved patients(P<0.05),and the apparent diffusion coefficient(ADC)was lower than those in improved patients(P<0.05).The areas under the ROC curve of FA value and ADC value predict the improvement of treatment in the observation group were 0.756 and 0.803,respectively,P<0.05.DTI fiber bundle reconstruction combined with intraoperative ultrasound has good value in the operation of gliomas in brain functional areas,which is worthy of clinical use.