丙泊酚复合舒芬太尼在腹腔镜子宫肌瘤剔除术中的应用效果分析

Application Effect Analysis of Propofol Combined with Sufentanil in Laparoscopic Myomectomy

目的:分析腹腔镜子宫肌瘤剔除术中丙泊酚复合舒芬太尼的应用效果。方法:选取北京市西城区展览路医院2019年2月-2021年5月收治的腹腔镜子宫肌瘤剔除术患者60例,按照随机数字法分为丙泊酚复合舒芬太尼组(舒芬太尼组)各30例、丙泊酚复合芬太尼组(芬太尼组),舒芬太尼组患者接受丙泊酚复合舒芬太尼静脉麻醉诱导,芬太尼组患者接受丙泊酚复合芬太尼静脉麻醉诱导,然后统计分析两组患者气管插管前、气管插管时、拔管时、拔管后的心率、血压、血氧饱和度;两组患者意识恢复时间、苏醒时间、定向力恢复时间;两组患者的不良反应发生情况。结果:气管插管前、气管插管时、拔管时舒芬太尼组患者的收缩压均显著低于芬太尼组,气管插管时、拔管时、拔管后时舒芬太尼组患者的舒张压均明显低于芬太尼组,气管插管时、拔管时舒芬太尼组的心率均显著低于芬太尼组,差异均有统计学意义(P<0.05)。舒芬太尼组的意识恢复时间、苏醒时间、定向力恢复时间均短于芬太尼组,差异有统计学意义(P<0.05)。舒芬太尼组患者的不良反应发生率低于芬太尼组,差异有统计学意义(P<0.05)。结论:腹腔镜子宫肌瘤剔除术中丙泊酚复合舒芬太尼的应用效果较丙泊酚复合芬太尼好。

Objective: To analyze the application effect of propofol combined with sufentanil in laparoscopic myomectomy. Methods: From February 2019 to May 2021, 60 patients with laparoscopic myomectomy in Exhibition Road Hospital in Xicheng District, Beijing were selected and divided into two groups according to random number table method, with 30 cases in each group: propofol combined with sufentanil group (sufentanil group), propofol combined with fentanyl group (fentanyl group). Patients in sufentanil group received propofol combined with sufentanil for intravenous anesthesia induction, and patients in fentanyl group received propofol combined with fentanyl for intravenous anesthesia induction. The heart rate, blood pressure, and blood oxygen saturation before tracheal intubation, during tracheal intubation, during extubation, and after extubation;the recovery time of consciousness, awakening time, and orientation recovery time;the occurrence of adverse reactions in the two groups of patients were statistically analyzed. Results: The systolic blood pressure of patients in the sufentanil group before tracheal intubation, during tracheal intubation, during extubation were significantly lower than those in the fentanyl group;The diastolic blood pressure of patients in the sufentanil group during tracheal intubation, during extubation, and after extubation were significantly lower than those in the fentanyl group;the heart rate of the sufentanil group during tracheal intubation and during extubation were significantly lower than those of the fentanyl group, and the differences were statistically significant (P<0.05). The recovery time of consciousness, awakening time, and orientation recovery time in the sufentanil group were shorter than those in the fentanyl group, and the differences were statistically significant (P<0.05). The incidence of adverse reactions in the sufentanil group was lower than that in the fentanyl group, and the difference was statistically significant (P<0.05). Conclusion: The application effect of propofol combined with sufentanil in laparoscopic myomectomy is better than that of propofol combined with fentanyl.