二陈汤加减联合肺康复训练治疗胸腔镜肺癌根治术后咳嗽

Modified Erchen Decoction Combined with Pulmonary Rehabilitation in Treating Cough After Thoracoscopic Radical Resection for Lung Cancer

目的:观察二陈汤加减联合肺康复训练治疗胸腔镜肺癌根治术后咳嗽患者的临床疗效。方法:选取80例胸腔镜肺癌根治术后咳嗽患者,按摸球法平均分为对照组和观察组。对照组给予复方甲氧那明+常规护理;观察组在对照组治疗基础上给予二陈汤+肺康复训练。比较两组患者临床疗效、中文版莱斯特咳嗽量表(mandarin Chinese version of the leicester cough questionnaire,LCQ-MC)评分、6分钟步行试验(6-minute walk test,6MWT)、肺功能[第1秒用力呼气量(forced expiratory volume in the first second,FEV1)、用力肺活量(forced vital capacity,FVC)及最大通气量(maximal voluntary ventilation,MVV)]、生活质量及术后恢复情况。结果:观察组有效率(100.0%)高于对照组(50.0%),差异有统计学意义(P<0.05)。观察组6MWT为(449.32±52.63)m,对照组6MWT为(388.10±43.41)m,两组比较,差异有统计学意义(P<0.05)。观察组Brog指数为(2.75±0.89)分,低于对照组的(3.70±1.01)分,差异有统计学意义(P<0.05)。观察组FEV1、FVC、MVV均高于对照组,差异均有统计学意义(P<0.05)。观察组圣乔治呼吸问卷评分为(32.85±6.24)分,低于对照组的(35.20±5.15)分(P<0.05)。观察组术后胸管留置时间、住院时间分别为(4.35±0.86)d、(12.65±2.76)d,均短于对照组的(5.80±1.22)d、(14.95±3.12)d,差异均有统计学意义(P<0.05)。结论:二陈汤加减联合肺康复训练治疗胸腔镜肺癌根治术后咳嗽患者疗效显著,可提高患者生活质量、运动耐力、肺功能,减轻咳嗽程度。

Objective:To observe the clinical effect of modified Erchen Decoction combined with pulmonary rehabilitation training in the treatment of cough patients after thoracoscopic radical resection of lung cancer.Methods:A total of 80 patients with cough after thoracoscopic radical resection of lung cancer were selected and divided into control group and observation group according to the touch-ball method.The control group was given compound methoxyphenamine+routine nursing;The observation group was given Erchen decoction+pulmonary rehabilitation training on the basis of the treatment of the control group.The clinical efficacy,Chinese version of the leicester cough questionnaire(LCQ-MC)score,6-minute walk test(6MWT),pulmonary function[Forced expiratory volume in the first second(FEV1),forced vital capacity(FVC)and maximal voluntary ventilation(MVV)]and quality of life and postoperative recovery were compared between the two groups.Results:The effective rate(100.0%)of the observation group was higher than that of the control group(50.0%),and the difference was statistically significant(P<0.05).The 6MWT of the observation group was(449.32±52.63)m,and the 6MWT of the control group was(388.10±43.41)m,the difference was statistically significant(P<0.05).The Brog index of the observation group was(2.75±0.89)points,which was lower than that of the control group(3.70±1.01)points,and the difference was statistically significant(P<0.05).The FEV1,FVC,and MVV of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).The score on St.George′s Respiratory Questionnaire in the observation group(32.85±6.24)was lower than that in the control group(35.20±5.15)(P<0.05).The postoperative chest tube indwelling time and hospital stay in the observation group were(4.35±0.86)d and(12.65±2.76)d,respectively,which were shorter than(5.80±1.22)d and(14.95±3.12)d in the control group,and the differences were all Statistical significance(P<0.05).Conclusion:Modified Erchen Decoction combined with pulmonary rehabilitation training has a significant curative effect in the treatment of cough patients after thoracoscopic radical resection of lung cancer,which can improve the patients′quality of life,exercise tolerance,lung function,and reduce the degree of cough.