摘要
目的 调查深圳市无偿献血人群中乙肝病毒(HBV)和丙肝病毒(HCV)的重叠感染情况。方法 2018年1-12月深圳市35 429名无偿献血者,用电化学发光检测乙肝表面抗原(HBsAg)和HCV抗体,并比较其性别、职业、既往手术史、吸烟饮酒史、HBV疫苗接种情况。结果 35 429名无偿献血者中检出124名HBV/HCV重叠感染、412名单纯HBV感染者、209名单纯HCV感染者。HBV/HCV重叠感染者中男性占比明显高于女性,性别比为2.1∶1。不同性别的感染类型差异均无统计学意义(P>0.05);HBV/HCV重叠感染者中,<20岁、20~<30岁、30~<40岁、40~<50岁、≥50岁的占比分别为4.03%、17.74%、41.94%、24.19%、12.10%,不同年龄献血者的感染类型差异无统计学意义(P>0.05);HBV/HCV重叠感染者中,大学及以上、高中、初中及以下占比分别为11.29%、22.58%、66.13%;学生、有固定职业人员、其他人员占比分别为30.65%、27.42%、41.94%,不同学历和职业献血人员的感染类型差异均无统计学意义(P>0.05);HBV/HCV重叠感染者中既往有手术史、烟酒史的占比分别是59.68%、55.65%,但差异无统计学意义(P>0.05);接种过HBV疫苗的献血者的HBV/HCV重叠感染占比低于未接种者,差异有统计学意义(P<0.01)。结论 2018年深圳市无偿献血人群中HBV/HCV重叠感染中男性、31~<40岁、低学历、无固定职业人员、既往手术史、吸烟饮酒史、未接种HBV疫苗者占比较高,需要针对上述情况加强防控。
Objective To investigate the overlapping infection of hepatitis B virus(HBV)/Hepatitis C virus(HCV)in unpaid blood donors in Shenzhen city. Methods From January to December 2018,there were 35 429 unpaid blood donors in Shenzhen city,Hepatitis B surface antigen(HBsAg) and HCV antibody were detected by electrochemiluminescence. The gender,occupation,previous operation history,smoking and drinking history and HBV vaccination were compared. Results Among 35 429 unpaid blood donors,124 HBV/HCV overlapping infection,412 HBV infection and 209 HCV infection alone were detected. The proportion of men in HBV/HCV overlapping infection was significantly higher than that of women,and the gender ratio was 2.1:1,without significant difference in infection types between different gender(P>0.05). Among the donors with HBV/HCV overlapping infection,the proportions of <20,20-<30,30-<40,40-<50 and ≥50 years old were 4.03%,17.74%,41.94%,24.19% and 12.10% respectively,without significant differences in infection types among blood donors of different ages(P>0.05). Among HBV/HCV overlapping infection,the proportions of college and above,high school,junior middle school and below were 11.29%,22.58% and66.13% respectively,and the proportion of students,personnel with fixed occupation and other personnel was 30.65%,27.42% and 41.94% respectively,without significant differences in the types of infection among blood donors with different educational background and occupations(P>0.05). The proportion of donors with HBV/HCV overlapping infection with previous operation history and smoking and alcohol history was 59.68% and 55.65% respectively,without significant difference(P>0.05). The proportion of HBV/HCV overlapping infection in blood donors inoculated with HBV vaccine was lower than noninoculation(P<0.01). Conclusion In 2018,among the unpaid blood donors in Shenzhen,male,aged 31-<40,with low educational background,without fixed occupation,previous operation history,smoking and drinking history,and not vaccinated with HBV vaccine accounted for a relatively high proportion of HBV/HCV over-lapping infection,so it is necessary to strengthen prevention and control.
作者
赖福堂
范树春
LAI Fu-tang;FAN Shu-chun(Shenzhen Longhua District People 5 Hospital Health Service Center,Shenzhen,Guangdong 518110,China)
出处
《中国国境卫生检疫杂志》
CAS
2022年第1期79-81,共3页
Chinese Journal of Frontier Health and Quarantine
关键词
无偿献血
乙肝病毒
丙肝病毒
重叠感染
Voluntary blood donation
Hepatitis B virus
Hepatitis C virus
Overlapping infection