血镁与尿毒症维持性透析患者生存预后关系的研究进展

Research progress on the relationship between serum magnesium and survival and prognosis of uremic maintenance dialysis patients

随着肾脏替代治疗技术的逐渐成熟,延长寿命及提高生活质量已经成为管理尿毒症患者的最终目标。近年来国内外多项研究提示,低镁血症可影响透析患者的预后,可能与死亡风险增加相关。我们从机制上了解血镁与血压、心血管疾病、骨代谢、血管钙化的相关性,指出血镁可能成为降低透析患者病死率的管控指标之一,挖掘其新的临床应用。

With the gradual maturity of renal replacement therapy technology,prolonging life span and improving quality of life of patients with uremia have become the ultimate management goals.In recent years,many studies at home and abroad have suggested that hypomagnesemia has an adverse effect on the prognosis of dialysis patients,which may be related to an increased risk of death.We understand the correlation between blood magnesium and blood pressure,cardiovascular disease,bone metabolism and vascular calcification,point out that blood magnesium may become one of the control indicators to reduce the mortality of dialysis patients,and explore its new clinical application.