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A promising strategy against SARS-CoV-2:pyrimidine inhibitors synergize with nucleoside analogues

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摘要 In a recent study published in Nature,David C.Schultz et al.demonstrated a new high-efficient therapy to fight against SARSCoV-2,that is,combining pyrimidine biosynthetic inhibitors with antiviral nucleoside analogues.1 By February 10,2022,SARS-CoV-2 has infected more than 400 million people,including more than 5.79 million deaths.Patients infected with SARS-CoV-2 usually develop mild to severe symptoms,and several patients lead to severe clinical outcomes.Although some vaccines or drugs have entered clinical practice,there is still a lack of effective antiviral therapy against the constantly changing virus.
作者 Long Min Qiu Sun
出处 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2022年第4期953-954,共2页 信号转导与靶向治疗(英文)
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