基于金纳米棒增强的银纳米团簇光电化学传感器在多巴胺检测方面的研究

MNBA-AgNCs Based Photoelectrochemical Sensors Enhanced by Gold Nanorods for Dopamine Detection

为了实现对多巴胺(dopamine,DA)的高精度检测,使用了具有5-巯基-2-硝基苯甲酸(5-mercapto-2-nitrobenzoic acid,MNBA)配体的Ag_(44)(SR)_(30)银纳米团簇(silver nanoclusters,Ag NCs)来制备光电化学(photoelectrochemical,PEC)传感器.实验结果表明,基于Ag NCs的PEC传感器表现出了良好的光电性能和对DA的传感性能,可以实现对DA的传感检测.为了进一步提高对DA的传感性能,将金纳米棒(gold nanorods,Au NRs)引入到Ag NCs中组成异质纳米材料,构建了基于Ag NCs/Au NRs的PEC传感器.实验结果表明,Au NRs的引入显著提高了Ag NCs的光电性能和传感性能,在0.84-6μmol/L DA浓度的线性范围内实现了2.94 n A/μmol·L^(-1)的灵敏度和0.28μmol/L的检测限(limit of detection,LOD),从而实现对DA的高精度检测.

Dopamine(DA)is extremely low in body and mainly exists in the central nervous system.DA is also closely related to many diseases of the nervous system.Therefore,high-sensitivity detection of DA is particularly important for the diagnosis and treatment of the diseases.The photoelectrochemical(PEC)sensors based on Ag_(44)(SR)_(30) silver nanoclusters(Ag NCs)with 5-mercapto-2-nitrobenzoic acid(MN-BA)ligands were first developed for high-sensitivity detection of DA.The experimental results showed that the PEC sensors based on Ag NCs exhibited photoelectric properties and sensing properties for DA.Then,hybrid nanomaterials by introducing gold nanorods(Au NRs)into Ag NCs were used to further improve sensing properties.The experimental results showed that Au NRs improved the photoelectric separation efficiency of Ag NCs and the catalytic performance for DA which significantly improved the photoelectric properties and sensing properties of the sensors.Ag NCs/Au NRs based PEC sensors achieved high sensitivity(2.94 n A/(μmol·L^(-1)))and low limit of detection(0.28μmol/L)in the linear range 0.84-6μmol/L DA concentration which demonstrated that enhanced Ag NCs/Au NRs based PEC sensors can be used for high-sensitivity detection of DA.